Only take the credit cards or travel cards you will use. Leave all other cards at home.
Research the laws about exchanging money, and, if you need extra money, only use official exchange facilities. Remember that First Interstate offers foreign currency services so you can prepare before you leave.
You may consider placing a stop or hold on your mail to help protect you against identity theft (an overflowing mailbox may also create the appearance that you're not at home).
Check the rules and common fees associated with your airline by visiting its website in advance.
Review what medical services your health insurance covers and consider medical travel insurance.
Pack a list of emergency phone numbers you may need while you're traveling. This may include the phone number of your credit card companies, your doctor's office, the US Embassy in the country you're visiting, and your airline.
Lessen the effects of jet lag by resetting your watch before you board your flight, drinking lots of water, and sleeping well before your trip.
To stay healthy, drink bottled water and use it to brush your teeth. Wash your hands and use hand sanitizer often.
If you haven't left your valuables at home, leave them in your hotel safe when you are out and about at your destination. Also leave your passport safe in the hotel rather than carrying it with you.